All New Bosses in the Binding of Isaac: Repentance

New horrors await in the cute but morbid world of The Binding of Isaac

All New Bosses in the Binding of Isaac Repentance

There is a good chance that you have at least tried the original rogue-lite game The Binding of Isaac, which defined the genre and changed the way we see indie games back in 2011. With a fair amount of challenge and ever-changing dungeons with many random power-ups to pick up along the way, each session with Isaac has always been a unique adventure.

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Binding of Isaac: Repentance, which arrived in 2021, brought so much new content, it made it seem like a completely new game. Being the final DLC for the legendary title, Repentance added:

  • Two new playable characters
  • 150+ new items
  • 100+ new enemies
  • Over 25 new bosses

There are even some fan-made bosses that made it into the expansion too. For the complete rundown of all the new fights in The Binding of Isaac: Repentance, keep reading.

All New Bosses in The Binding of Isaac: Repentance

Not only have new fights been added to existing areas, but there’s also some new zones for you to check out too.

New Bosses Added to Existing Areas in The Binding of Isaac: Repentance

  • Baby Plum – Found in The Basement, Cellar, and Burning Basement / Base HP: 234
  • Bumbino – Found in The Caves / Base HP: 385
  • Great Gideon – Found in The Caves, the Catacombs, and Flooded Caves / Base HP: Wave-based fight
  • Tuff Twins – Found in The Caves, the Catacombs, and Flooded Caves / Base HP: 35
  • The Shell – Found in The Caves, the Catacombs, and Flooded Caves / Base HP: 35
  • Singe – Found in The Caves, the Catacombs, and Flooded Caves / Base HP: 444
  • Reap Creep – Found in The Caves and the Depths / Base HP: 690
  • The Pile – Found in The Caves, the Catacombs, Flooded Caves, and Necropolis / Base HP: 580

New Bosses in the Mausoleum and Gehenna in The Binding of Isaac: Repentance

  • The Siren – Found in the Mausoleum / Base HP: 666
  • The Heretic – Found in the Mausoleum / Base HP: 789
  • The Visage – Found in Gehenna / Base HP: 620
  • The Horny Boys – Found in Gehenna / Base HP: 707

Bosses in Downpour & Dross in The Binding of Isaac: Repentance

  • The Rainmaker – Found in Downpour / Base HP: 200
  • Lil Blub – Found in Downpour and Dross / Base HP: 130
  • Min Min – Found in Downpour / Base HP: 280
  • Wormwood – Found in Downpour and Dross / Base HP: 200
  • Clog – Found in Dross / Base HP: 420
  • Colostomia – Found in Dross / Base HP: 380
  • Turdlet – Found in Dross / Base HP: 190

Bosses in Alternative Corpse in The Binding of Isaac: Repentance

  • Rotgut – Found in Corpse / Base HP: 1800
  • Chimera – Found in Corpse / Base HP: 1050
  • The Scourge – Found in Corpse / Base HP: 950
  • Mother – Found in Corpse / Base HP: 4222

New Bosses in Home in The Binding of Isaac: Repentance

Dogma – Found in Home / Base HP: 2400
Ultra Famine – Found in Home / Base HP: 2000
Ultra Pestilence – Found in Home / Base HP: 1800
Ultra War – Found in Home / Base HP: 2000
Ultra Death – Found in Home / Base HP: 2000
The Beast – Found in Home / Base HP: ???

And that’s all the bosses in the last DLC for The Binding of Isaac – Repentance! Good luck beating them all to get that final true ending, at long last.

For more indie games, check out Dead Cells New “Everyone Is Here” Update Brings Indie Classics To The Game.

About the Author

Nikola "Nick" Jovanovic

Nick has been a Prima Games Staff Writer since May 2022, an old-school gamer, and a gamer journalist with over 25 years of expertise. Our resident micro-influencer from Serbia! When he's not driving through Belgrade, he's probably racing in Gran Turismo or Forza, playing some strange JRPG games or just watching pro wrestling.